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The BIOFIRE System and Your Immune System The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare providers to select the appropriate test first time. Patients benefit from quicker diagnosis and more specific treatment. Clinicians benefit from improved stewardship of antibiotics. Labs improve efficiency and cost savings. bio ethanol fireplace suite Plus Panel (PN panel) analyzes native sputum (including mini-BAL) as well as endotracheal sludge and bronchoalveolar liquids (including mini BAL) for 33 clinically significant pathogens and resistance genes to antimicrobials within one hour. Respiratory The burning of biomass (wood, plants and other organic material) produces gaseous pollutants and fine particulate matter that adversely affect the respiratory system. Additionally, the environmental issues caused by forest fires, like droughts, could be amplified by climate change, thereby increasing their negative impact on human health. In the United States, wildfire smoke has been linked to hospitalizations for respiratory illnesses, including asthma, COPD and lung cancer. In addition, this type of air pollution can be a risk factor for cardiovascular disease and is a significant contributor to the burden of illness among the most vulnerable populations, including people who are of lower socioeconomic status (SES). During the COVID-19 pandemic, many communities were exposed to harmful levels of air pollution from wildfires. The response of public health has been limited to a communication campaign about managing symptoms. This gap in knowledge is alarming given the evidence of potential health risks resulting from the continual exposure to smoke and other sources of poor air quality. Researchers are now looking at how to best protect the public's health during future incidents of this type. NIH funds research on this important public health issue through the BLUE CORAL and FIRE CORAL studies. For the first time an prospective cohort study will examine long-term effects resulting from exposure to smoke from wildfires and other sources. FIRE CORAL is a study that seeks adult participants who are admitted to hospital for COVID-19 index episodes and who speak English or Spanish, but are not pregnant. The Fire Coral protocol includes a series of in-person assessments that objectively measure the pulmonary function testing lung imaging and functional assessment. The lungs are particularly sensitive to the effects of smoke and other particles due to the fact that they can trigger or exacerbate chronic respiratory conditions such as emphysema, asthma and COPD, and increase the risk of contracting pneumonia. Smoke exposure can have negative effects on your health. To lessen or stop these effects, you should avoid outdoor activities and wear the EPA “N95” mask. The mask is designed to trap fine particles. Smoking can cause irritation to the throat and eyes, and can cause an irritated nose. To help reduce symptoms, drink plenty of water, and take medications that reduce inflammation, such corticosteroids. Bloodstream Your bloodstream is at the forefront of fighting germs that enter your body. Dendritic cells are specialized cells that are akin to your fire department's call center. they gather antigens (molecules that trigger an immune response) from germs that are invading your body and release proteins that alert other white blood cells to come fight them. Circulating total white blood cells, differentials, and band cells were elevated after firefighters' firefighting shifts, and compared to levels following strenuous physical exercise with no firefighting. Skin As the wildfires in California spewed smoke and ash into the air this past winter and fall, dermatologists were concerned about how that could affect the skin of people exposed to it. Maria Wei is a graduate student from University of California, Irvine. She studies how extreme wildfire pollution affects the skin. Her research was published in Scientific Reports on April 22. The research of Wei shows that the temperature of the skin changes based on the length of time that the body is exposed to flames. It takes upwards of two hours for a skin to reach its flash point, the place where it begins to burn and then turns ashy. It's important not to stay near a fire pit or campfire, and you should always wear protective clothing when out during a hot or humid day. Forest fires will continue occur, despite the measures taken to stop fires from causing pollution. Wei is forecasting that the number of people suffering from the effects of wildfires will grow as climate change causes more forests to be burned. This means that more people will have to wear long sleeves and hats as well as thick moisturizers. The air pollution from wildfires can exacerbate atopic skin dermatitis, which is a condition that causes itchy skin for many people. The reason for this is due to the particles in smoke can clog pores, thereby making the atopic dermatitis condition worse. Another issue is the fact that atopic dermatitis can make people more sensitive to UV light, which may be aggravated by wildfire smoke. This makes people more likely to visit tanning salons, and can also cause them to tan with less protection than they ought to. A treatment with ice and fire could help to reduce atopic dermatitis symptoms however it is not recommended for anyone with an open wound or rash. This treatment is not recommended for people who have active acne, or if you are pregnant or nursing. The IS Clinical Fire & Ice Facial, at Novuskin Las Vegas' premier membership MedSpa is a result-driven, intensive facial that bridges between the mild facelift and the peel, with no downtime. It's designed to resurface the skin, improve rosacea symptoms, decrease acne scarring, reduce lines and wrinkles, and stimulate cellular renewal. This is a great way to give your skin a glowing glow. Infections The human body is a complicated network of organs and tissues that work to protect us from infection. Infections can be caused by microorganisms, such as parasites, viruses, and bacteria that infect healthy cells and cause them to multiply in uncontrolled ways. When this happens, your immune system may respond with symptoms of illness. These symptoms could range from a swollen or achy nose to a stomach upset and can include a fever high, swollen glands, and an rash. The type of infection and the location can affect your symptoms. Infections can be spread through a variety of methods but the most prevalent are from person to person via droplets that remain in the air after coughing or sneezing. Bacterial diseases such as strep throat, tuberculosis, meningococcal diseases and Legionnaires disease spread this way, along with some viral infections, such as the common cold and influenza. Some bacterial infections such as skin infections or sexually transmitted diseases (STIs) such as chlamydia or gonorrhea are transmitted through direct contact with infected mucous surfaces or tissues, or indirectly through contaminated surfaces. Some bacterial diseases are transmitted by bugs like mosquitoes, ticks or fleas, and are transmitted when they bite you. Infections, parasites, and other microorganisms are tiny enough to be able to get into your bloodstream and infect your cells. This can lead to serious diseases like the common cold or AIDS. Fungi cause many skin conditions such as ringworm and athlete's foot, while some are a threat to the lungs and nervous system, such as the rabies virus. The BioFire Panel utilizes our unique FilmArray technology to analyze sputum and bronchoalveolar fluid samples for a comprehensive listing of pathogens involved in upper respiratory infections. The kit includes an reagent pouch that houses all the necessary chemistry to perform reverse transcription PCR, nested multiplex analysis and detection on a single machine. This is a straightforward solution that helps clinicians identify and treat patients with several respiratory symptoms. This test has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.